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What Gets You High?

The Endocannabinoid System or ECS

You may not know that humans have an entire system in our body named after weed – our endocannabinoid system. “Endo” is short for “endogenous” meaning inside your body, and “cannabinoid” comes from “cannabis”. It was named like this because the substances found in the cannabis plant were discovered first and named cannabinoids; it was later discovered the human body produces its own substances that are molecularly similar. 

The ECS is the network of receptors, endocannabinoids and enzymes that help our bodies control a myriad of health factors, from appetite and metabolism to mood and stress. The ECS works to maintain homeostasis—or equilibrium—by keeping your internal environment stable, no matter what is happening outside your body. This network of receptors is all over your body, with notable concentrations of receptors in your brain and along your digestive tract, depicted below:

The discovery of anandamide, the human body’s own endogenous cannabinoid, is thanks to cannabis research that took place as early as the 1960s. It has been dubbed “the bliss molecule”, for the role that it plays in mood, appetite, sleep and even memory loss. Its molecular resemblance to THC makes it a point of interest to many scientists and researchers, as it may help us understand how cannabis can be beneficial for the human body.  

It wasn’t until 1988 in a government-funded study at the St. Louis University School of Medicine that Allyn Howlett and William Devane determined that the mammalian brain has receptor sites that respond to compounds found in cannabis. These receptors, named cannabinoid receptors turned out to be the most abundant type of neurotransmitter receptor in the brain!

There are two broad types of cannabinoid receptors that researchers are aware of: CB1 and CB2. CB1 receptors are found mostly in the brain and in the nerves of the spinal cord; they help to moderate memory, mood, perceptions of pain and motor functions. CB1s are also what allow for the psychoactive effects of THC when it binds to them. CB2 receptors abound in the immune system, and also exist in the digestive system and the extremities. They help control inflammation. Different cannabinoids bind to these sites in different ways, which create different effects in the body. 

Here are a few types of cannabinoids that we will expand upon in future posts and link back here:

  • THC (Tetrahydrocannabinol)
  • CBD (Cannabidiol)
  • CBG (Cannabigerol)
  • CBN (Cannabinol)

Disclaimer: This article is not a substitute for professional medical advice, diagnosis, or treatment. Always consult with your doctor or other licensed medical professional. Do not delay seeking medical advice or disregard medical advice due to something you have read on this website.


White Label | Rainbow Crush

Total Cannabinoids: 91.13%

THC: 78.87%

CBD: 0.16%

Main Terps: Caryophyllene, Limonene, Myrcene, Humulene


Fruity with a floral after taste. It stuck with me a bit, which was nice. I really enjoyed the mix of flavors dabbing this gave. 


I didn’t necessarily feel glued to the couch from this extract, but more comfortable yet extremely awake. It made for a perfect gaming 710 sesh. 

All in All

I Highly Recomend This Dab

CBDiscovery | Blue Magoo x Pearl OG

CBDiscovery Infused pre roll – Blue Magoo x Pearl OG

THC: 304.74

CBD: 0.72 mg

The label says ‘Extremely High Potency. Not for beginners.’ and it should be heeded.

We found it to be a very smooth flavorful smoke that burned evenly, which can be difficult to find with infused pre-rolls. We did need to put the last third into a bowl to finish the rest off as the oil made it difficult to draw on, but it was totally worth it.

Very nice effect and most definitely not for beginners.

Drop Science Shorties | Forum GSC

Product: Drop Science – Shorties 1g Full Spectrum C02 Vape Cartridge

Strain Information: Forum GSC (Indica)

THC: 71.2 % 

CBD: 0.20 %

Budtender’s Review: Nug-run, single source, full spectrum C02 cartridge. No additives & no fake terpenes. Tasted sweet and hoppy with a hint of pepper.  Smooth hitting cartridge. Overall nice high but not very heavy. They include a optional “strain sticker” with the package so you can differentiate your strains if you have multiple. I would consider this a top shelf cartridge. I definitely enjoyed this one.  

CBDiscovery | Banana Punch

2.53% CBG
3.10% Terps

Super good flavor on this one. Definitely banana! And the high has a nice heavy body high with that CBG in it. Still very heady though!

Packaging could be glass instead of plastic
It would be nice to see which terpenes are in there and not just the percentage 

Sugar crumble, very soft not too sticky, maybe a little dry

Bananas. Definitely floral and sweet with a little bit of some hops or weed flavor

Overall very flavorful, and just a great high for CBDiscovery. They usually do a pretty good job. I’m pretty impressed

I’d recommend this flavor to anyone who likes sweet floral flavors

Marijuana & Our Health

Since 2013, Dr. Sanjay Gupta, CNN’s chief medical correspondent, has done very public advocacy for the legitimacy of marijuana. In case you’ve missed this groundbreaking coverage of cannabis, we have gathered some highlights to help familiarize yourself with how far we have come as a society to overcome the stigma and misinformation of “reefer madness”! Here’s a clip of Dr. Gupta speaking about how cannabis is safer than narcotics:

On Sunday, April 19, 2015, CNN premiered WEED 3: The Marijuana Revolution, a special report by Dr. Sanjay Gupta about the politics of medical marijuana research, with a special focus on MAPS and Dr. Sue Sisley’s work to study medical marijuana for U.S. veterans with posttraumatic stress disorder (PTSD). The documentary follows Doblin and Sisley as they work to conduct the first clinical study of medical marijuana for PTSD, illustrating how the study has had to overcome numerous obstacles including the Public Health Service (PHS) review process and the National Institute on Drug Abuse (NIDA) monopoly on marijuana approved for clinical research.” – from

Some of Dr. Gupta’s 2015 work is nicely highlighted here.

In 2019, Dr. Gupta started to once again implore the US Attorney General to further consider how marijuana can help the United States overcome our massive opioid abuse crisis. Here’s a clip:

All of the latest contributions to CNN by Dr. Gupta on the topic of the health benefits of marijuana have been gathered here.

Thank you & for hosting this important information!

Dirty Arm Farm Hat Giveaway!

One gram of Dirty Arm Farm Hater Tears Live Resin in our inventory has been specially marked inside with a “Magic Ticket” that will award the lucky buyer with a very special Dirty Arm Farm hat!!!

Come in today and pick up some fire Dirty Arm Farm grams for your chance at this coveted hat.

EDIT: Congrats to our winner!!!!




#medford #dispensary #dirtyarmfarm #giveaway #swag #hatertears #liveresin #cannabis #thc

Strain Review: Chem Sour Blueberry Snow

Chem Sour Blueberry Snow by Chronic Cultures
Sativa Dominant Hybrid (60% Sativa 40% Indica)
A cross of Chemdawg/Sour Diesel/Blueberry/Oregon Snow

Budtender’s Review
As soon these buddlets dropped, I knew I had to try them.
When I opened the container of this strain, the diesel smell hit me hard followed by a hint of blueberry. It was absolutely mouthwatering!
The first hit I took was a doozy, the sour diesel taste was strong but not as sour as I was expecting. The blueberry comes in as a sweet aftertaste making you crave blueberry muffins afterwards.
This strain felt like the best of both worlds. as soon as I exhaled I felt an extreme sense of Euphoria yet also extremely relaxed. After 3 bowls of this I felt like I was exploring another world picking blueberries. It was perfect for a long gaming adventure!
#PositiveVibes #letsgethigh #thespot #cannabiscollective #budisbest #shattermatters #dabsfordays #highlife #weedlove #fueledbybho #dabbersdigest #dailycannabiz #kushfam #positivityisalifestyle #choosehappiness #hightimes #medicated #kosherkush #chroniccultures #budtender #dispensary #medford

originally written by Paige Spencer, posted by VW

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